Physiological Effects of Different Thoracolumbar Transspinal Stimulation Electrode Configurations in Humans

Jun 12, 2022·
Andreas Skiadopoulos
Andreas Skiadopoulos
,
Rachel Burau
,
Stephan Heddon
,
Nicole Saulnier
,
Timothy S. Pulverenti
,
Maria Knikou
· 0 min read
Abstract
This poster reports on the study later published as “Physiological effects of cathodal electrode configuration for transspinal stimulation in humans” (see the linked journal article). We established the neurophysiological properties of transspinal evoked potentials (TEPs) in response to four configurations of the cathode electrode — a rectangular electrode (P-KLAB4Recovery), a square electrode (P-2), two square electrodes 1 cm apart placed at midline (P-3), and a square electrode placed on each paravertebral side (P-4) — recorded bilaterally from ankle and knee muscles. TEP onset latency differed significantly across muscles and protocols, and P-4 required a rightward shift in stimulation intensity to evoke TEPs of similar amplitude to the other configurations. The findings support selecting a stimulation configuration for transspinal stimulation studies based on this physiological evidence. Supported by NIH/NICHD (R01 HD100544) and NYSDOH/SCIRP (C35594GG).
Date
Jun 12, 2022 — Jun 16, 2022
Event
International Motoneuron Society (IMNS) Meeting 2022
Location

Banff Centre

Banff, AB